SS-31
Mitochondria-targeted tetrapeptide (Elamipretide) for cardiolipin stabilization and cellular energy research
Select size
For research purposes only. Not for human consumption.
Mechanism of Action
SS-31 (Elamipretide, also known as Bendavia or MTP-131) is a mitochondria-targeted tetrapeptide (D-Arg-2',6'-dimethylTyr-Lys-Phe-NH₂) that selectively concentrates in the inner mitochondrial membrane, where it binds cardiolipin to stabilize cristae structure and optimize electron transport chain function.
How It Works
- 1
Selectively binds cardiolipin in the inner mitochondrial membrane, preserving cristae architecture
- 2
Stabilizes electron transport chain super-complexes to enhance ATP production efficiency
- 3
Reduces mitochondrial reactive oxygen species (ROS) generation and oxidative stress
- 4
Prevents cytochrome c peroxidase activity that drives apoptosis in stressed cells
- 5
Restores mitochondrial bioenergetics in aged, ischemic, and dysfunctional tissue models
Key Research Benefits
- Mitochondrial function research
- Cardiolipin stabilization studies
- Cellular energy (ATP) production
- Oxidative stress reduction
- Cardiac and skeletal muscle bioenergetics
- Aging and neurodegenerative pathway exploration
SS-31 has been studied across cardiovascular, renal, neurological, and skeletal muscle research models for its ability to restore mitochondrial function in age-related and ischemia-reperfusion injury contexts. Each vial contains 10mg of lyophilized peptide. Reconstitute with bacteriostatic water and store refrigerated (2–8°C) post-reconstitution. For research use only — not for human consumption.