Thymosin Alpha-1
Thymic 28-amino acid peptide (Tα1) for T-cell maturation, innate/adaptive immune modulation, and immune-senescence research
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For research purposes only. Not for human consumption.
Mechanism of Action
Thymosin Alpha-1 (Tα1) is a 28-amino acid acetylated peptide originally isolated from thymic tissue that modulates innate and adaptive immunity by acting on toll-like receptors (primarily TLR2 and TLR9) on dendritic cells, promoting T-cell maturation, and enhancing pathogen-recognition pathways.
How It Works
- 1
Binds TLR2/TLR9 on dendritic cells and monocytes to drive Th1-polarized cytokine profiles
- 2
Promotes maturation of CD4+ and CD8+ T-cells from thymic precursors
- 3
Enhances natural killer (NK) cell cytotoxic activity and interferon signaling
- 4
Modulates regulatory T-cell (Treg) balance and reduces chronic inflammatory tone
- 5
Studied for restoring immune competence in aged or immunocompromised research models
Key Research Benefits
- T-cell maturation and immune modulation research
- Innate immunity (TLR pathway) investigation
- Age-related immune-senescence models
- Chronic viral and inflammatory research applications
- Vaccine adjuvant and NK-cell activity studies
Thymosin Alpha-1 (Tα1) has been studied extensively in infectious disease, oncology, and immune-senescence research models. Each vial contains 10mg of lyophilized peptide. Reconstitute with bacteriostatic water and store refrigerated (2–8°C) post-reconstitution. For research use only — not for human consumption.